GÖREV ALDIĞI BÖLÜMLER
GÖZ HASTALIKLARI
Correlations of Corneal Optical Densitometry, Endothelial Hexagonality Percentage, and Epithelium Thickness
By
Pekel, G (Pekel, Gokhan) [1] ; Özbakis, F (Ozbakis, Fatih) [1] ; Bahar, A (Bahar, Alperen) [1] ; Pekel, E (Pekel, Evre) [2] ; Çetin, EN (Cetin, Ebru Nevin) [1]
(provided by Clarivate)
Source
Volume
43
Issue
2
Page
170-174
DOI
10.1080/02713683.2017.1387271
Published
2018
Indexed
2018-03-29
Document Type
Article
Abstract
Purpose: Our aim was to examine the associations between the cornea morphological parameters, endothelial cell density, and anterior chamber measurements.
Methods: This observational study included 50 eyes of 50 healthy volunteers. The thicknesses of corneal epithelium, Bowman's layer, stroma, Descemet's membrane-endothelium complex, and pre-ocular tear film were measured by means of anterior segment optical coherence tomography. The keratometry (K), corneal volume (CV), corneal optical densitometry (COD), iridocorneal angle (ICA), anterior chamber depth (ACD), and anterior chamber volume (ACV) measurements were taken by the Scheimpflug anterior segment imaging. The corneal endothelial cell density and percentage of hexagonality were measured by specular microscopy.
Results: The COD was only correlated with the thickness of Bowman's layer (r = -0.30, p = 0.035). The hexagonal endothelial cell percentage was correlated with the thickness of the pre-ocular tear film (r = -0.50, p < 0.001), ACD (r = 0.40, p = 0.004), and ACV (r = 0.34, p = 0.015).
The corneal epithelium thickness was associated with the ACD (r = 0.30, p = 0.034), ACV (r = 0.34, p = 0.018), K-flat (r = -0.35, p = 0.013), and K-steep (r = -0.29, p = 0.038) readings.
Conclusions: The anterior chamber morphological parameters (i.e., ACV, ACD) were significantly positively correlated with the hexagonal endothelial cell percentage and corneal epithelium thickness in healthy adults.
Keywords
Author Keywords
Corneal densitometry hexagonal cells epithelium thickness anterior chamber volume Bowman's layer
Posterior pole asymmetry analysis and retinal thickness measurements in young relatives of glaucoma patients
By
Pekel, G (Pekel, Gokhan) [1] ; Acer, S (Acer, Semra) [1] ; Yagci, R (Yagci, Ramazan) [1] ; Kaya, H (Kaya, Huseyin) [1] ; Özbakis, F (Ozbakis, Fatih) [1] ; Bahar, A (Bahar, Alperen) [1] ; Çetin, EN (Cetin, Ebru Nevin) [1]
(provided by Clarivate)
Source
KAOHSIUNG JOURNAL OF MEDICAL SCIENCES
Volume
31
Issue
8
Page
420-425
DOI
10.1016/j.kjms.2015.06.001
Published
AUG 2015
Indexed
2015-08-17
Document Type
Article
Abstract
The presence of a family history of glaucoma is a known risk factor for primary open-angle glaucoma (POAG) in middle-aged and older individuals. In this study, our aim was to demonstrate possible early glaucomatous alterations in young first-and second-degree relatives of POAG patients by spectral-domain optical coherence tomography. A total of 104 participants (52 relatives of POAG patients and 52 healthy individuals) were recruited in this cross-sectional study. All the participants were between 17 years and 45 years of age. All eyes underwent testing with spectral-domain optical coherence tomography. Peripapillary retinal nerve fiber layer thickness, hemifield macular thickness, macular ganglion cell complex thickness, posterior pole asymmetry analysis, and retinal arteriolar caliber measurements were taken for comparison between the study and control groups. The mean peripapillary retinal nerve fiber layer thickness was 104.9 +/- 8.8 mm in the study group and 105.6 +/- 7.4 mm in the control group (p = 0.68). Although whole macular thickness measurements were higher in the control group when compared with the study group (p = 0.008), the macular ganglion cell complex thickness was similar in both groups (p = 0.87). The posterior pole asymmetry analysis revealed no statistically significant difference between the groups in the aspect of consecutive black squares (p = 0.79). The mean retinal arteriolar caliber was 85.9 +/- 4.8 mm in the study group and 86.0 +/- 5.0 mm in the control group (p = 0.90). In conclusion, young relatives of POAG patients do not show characteristic glaucomatous damage when compared with the controls. Copyright (C) 2015, Kaohsiung Medical University. Published by Elsevier Taiwan LLC. All rights reserved.
Keywords Ganglion cell complex Posterior pole asymmetry analysis Primary open-angle glaucoma Retinal
Macular asymmetry analysis in sighting ocular dominance
By
Pekel, G (Pekel, Gokhan) [1] ; Acer, S (Acer, Semra) [1] ; Özbakis, F (Ozbakis, Fatih) [1] ; Yagci, R (Yagci, Ramazan) [1] ; Sayin, N (Sayin, Nihat) [2]
(provided by Clarivate)
Source
KAOHSIUNG JOURNAL OF MEDICAL SCIENCES
Volume
30
Issue
10
Page
531-536
DOI
10.1016/j.kjms.2014.08.003
Published
OCT 2014
Indexed
2014-12-03
Document Type
Article
Abstract
Sighting ocular dominance is the preference of one eye over the other in terms of sighting. In this study, our aim was to examine differences in interocular and intraocular macular thickness, interocular fovea-optic disc angle, and foveal blood vessel asymmetries associated with sighting ocular dominance. Ninety eyes of 45 healthy young adults were included in this prospective, cross-sectional, and comparative study. Sighting ocular dominance was determined by a hole-in-the-card test. Macular thickness measurements were taken and posterior pole asymmetry analysis conducted with spectral domain optical coherence tomography. The optic disc-fovea angle and visible foveal blood vessel counts were calculated by using the posterior pole retinal images of optical coherence tomography. The mean age of the participants was 27.3 (standard deviation [SD] 6.6) years. There were 20 males and 25 females. The mean total macular area thickness, and mean macular thickness of the superior and inferior hemispheres of the dominant and nondominant eyes were similar (p > 0.05). Macular asymmetry analysis revealed no statistically significant interocular difference (p > 0.05). In the dominant eyes, the mean optic discefovea angle was 5.24 degrees (SD 1.77), whereas it was 5.49 degrees (SD 2.58) in the nondominant eyes (p = 0.51). The number of visible blood vessels passing through the fovea was similar in the dominant and nondominant eyes (p > 0.05). These results suggested that interocular and intraocular macular thickness differences, interocular fovea-optic disc angle differences, and number of visible foveal blood vessels are not associated with sighting ocular dominance. Copyright (C) 2014, Kaohsiung Medical University. Published by Elsevier Taiwan LLC. All rights reserved.
Keywords
Author Keywords
Fovea-optic disc angle Foveal blood vessels Macular thickness Posterior pole asymmetry