İdari Görevler:

30.12.2004 – 16.07.2023       Anabilim Dalı Başkanlığı

Mustafa Kemal Üniversitesi/ Tayfur Ata Sökmen Tıp Fakültesi/ Cerrahi Tıp Bilimleri Bölümü/ Kadın Hastalıkları ve Doğum Anabilim Dalı         

01.01.2004 – 01.01.2007       Fakülte Yönetim Kurulu Üyeliği

Hatay Mustafa Kemal Üniversitesi/ Tayfur Ata Sökmen Tıp Fakültesi/ Cerrahi Tıp Bilimleri Bölümü/ Kadın Hastalıkları ve Doğum Anabilim Dalı         

18.01.2004 – 26.10.2006       Başhekimlik

Mustafa Kemal Üniversitesi/ Tayfur Ata Sökmen Tıp Fakültesi/ Cerrahi Tıp Bilimleri Bölümü/ Kadın Hastalıkları ve Doğum Anabilim Dalı 

ÖDÜLLER

1. EN İYİ POSTER BİRİNCİLİK ÖDÜLÜ; Leep Uygulanan Olguların Servikal PAP Smear Ve Biopsi Bulgularının Karşılaştırması., IV. Ulusal Sitopatoloji Kongresi., 2009
2. EN İYİ POSTER ÜÇÜNCÜLÜK ÖDÜLÜ; Hatay Yöresinde Fetal Anomalilerde Otopsi Bulguları., 19. Ulusal Patoloji Kongresi GİRNE KIBRIS, KUZEY KIBRIS TÜRK CUMHURİYETİ, 2009
3. EN İYİ MAKALE BİRİNCİLİK ÖDÜLÜ; Ratlarda İntraoküler Endometriozis Modeli, Türk Fertilite Dergisi, 1996
4. Menstrual disorders and pelvic pain after sterilization. Advances in Contraception, DİCLE ÜNİVERSİTESİ, 1995
5. Changes in ovarian function after tubal sterilization. Advances in Contraseption, DİCLE ÜNİVERSİTESİ, 1994
6. Hygroscopic cervical dilators in eclampsia, DİCLE ÜNİVERSİTESİ, 1993

DÜZENLEDİĞİ KONGRELER VE KONGRE BİLİMSEL KURUL ÜYELİĞİ:

1.         ALİ ULVİ HAKVERDİ (2009) Jinekolojik Onkoloji Bölgesel Toplantıları- Endometrium Kanserleri ve Servikal Sitoloji Sempozyumu 20 Kasım ANTAKYA –HATAY (MODERATÖR)

2.         ALİ ULVİ HAKVERDİ (2008). Mustafa Kemal Üniversitesi 2. Ürojinekoloji günleri 29-30 Kasım ANTAKYA –HATAY (MODERATÖR)

3.         HAKVERDİ ALİ ULVİ (2010). Ürojinekolojide Tartışmalı Konular Sempozyumu (BİLİMSEL KURUL ÜYELİĞİ)

4.         HAKVERDİ ALİ ULVİ (2007). Hatay MKÜ Ürojinekoloji Günleri -I  4-5 Mayıs ANTAKYA HATAY(MODERATÖR)

5.         ALİ ULVİ HAKVERDİ (2008) II. Hatay Perinatoloji Günleri. 11-12 Ekim HATAY ( MODERATOR)

OTURUM BAŞKANLIKLARI

1.         HAKVERDİ ALİ ULVİ (2007). Hatay MKÜ Ürojinekoloji Günleri -I  4-5 Mayıs ANTAKYA HATAY 3. Oturum Başkanı

2.         ALİ ULVİ HAKVERDİ (2008) II. Hatay Perinatoloji Günleri. 11-12 Ekim HATAY Açılış konuşması ve 4. Oturum Başkanı.

3.         ALİ ULVİ HAKVERDİ (2009) III. Hatay Perinatoloji Günleri. 03  Ekim HATAY Açılış konuşması ve Oturum Başkanı.

4.         ALİ ULVİ HAKVERDİ (2009) IV. Ulusal Ürojinekoloji Günleri. 21-24 Ekim İSTANBUL. 7. Oturum Başkanı

5.         ALİ ULVİ HAKVERDİ (2008). Mustafa Kemal Üniversitesi 2. Ürojinekoloji günleri 29-30 Kasım 1. Oturum Başkanı

6.         ALİ ULVİ HAKVERDİ (2010). Jinekolojik Onkoloji Derneği, Çukurova Bölgesel Toplantı 26-27 Haziran. ADANA 5. Oturum Başkanı

1. ESERLER

Uluslararası hakemli dergilerde yayımlanan makaleler:

1. SOYLU KARAPINAR OYA,GÖZÜKARA İLAY,HAKVERDİ ALİ ULVİ,GÜNGÖREN ARİF (2017). A new

marker for the prediction of mean platelet volume, placenta previa and placental invasion

anomalies. Perinatal journal, 1(25), 32-37., Doi: 10.2399/prn17.0251007 (Yayın No: 3469787)

2. SOYLU KARAPINAR OYA,GÜNGÖREN ARİF,DOLAPÇIOĞLU KENAN SERDAR,BENK ŞİLFELER

DİLEK,KESKİN KURT RAZİYE,HAKVERDİ ALİ ULVİ (2016). Does the presence of anhydramnios affect

the duration of medical abortion. Ginekologia Polska, 87(9), 635-638., Doi: 10.5603/GP.2016.0058

(Yayın No: 3328686)

3. KESKİN KURT RAZİYE,GÜLER OKYAY AYŞE,HAKVERDİ ALİ ULVİ,GÜNGÖREN ARİF,DOLAPÇIOĞLU

KENAN SERDAR,karateke atilla,Dogan Mustafa Ozcil (2015). The effect of obesity on inflammatory

markers in patients with PCOS a BMI matched case control study. Archives of Gynecology and

Obstetrics (Yayın No: 2437437)

4. GÖZÜKARA İLAY,SOYLU KARAPINAR OYA,HAKVERDİ ALİ ULVİ,DOLAPÇIOĞLU KENAN SERDAR,BENK

ŞİLFELER DİLEK,ÖZÇİL MUSTAFA DOĞAN,KESKİN KURT RAZİYE,GÜLER OKYAY AYŞE,GÜNGÖREN

ARİF (2015). Evaluation of conservative and radical surgical outcomes in placenta previa and

accreta cases. Perinatal Journal, 23(3), 148-152., Doi: 10.2399/prn.15.0233002 (Yayın No:

3384692)

5. ÇULHA GÜLNAZ, GÜNGÖREN ARİF, DEMİR CEMİL, HAKVERDİ ALİ ULVİ, DURAN NİZAMİ (2015).

Detection of Trichomonas Vaginalis in Vaginal Speciemens

from Women by Wet Mount, Culture and PCR. Journal of Clinical and Analytical Medicine, 6(5), 537-

540., Doi: 10.4328/JCAM.2158 (Yayın No: 8392219)

6. KARATEKE ATİLLA,BENK ŞİLFELER DİLEK,GÜNGÖREN ARİF,KESKİN KURT RAZİYE,GÜLER OKYAY

AYŞE,DOKUYUCU RECEP,ULUTAS TURKER,UN BURAK,PAKSOY HACER,HAKVERDİ ALİ ULVİ (2015).

Can the ductus venosus doppler predict the hemoglobinopathies?. Int J Clin Exp Med. (Yayın No:

3411066)

7. KESKİN KURT RAZİYE, PINAR NESLİHAN, KARATEKE ATİLLA, GÜLER OKYAY AYŞE, BENK ŞİLFELER

DİLEK, ALBAYRAK AYNUR, ÖZDEMİR SEMRA, HAKVERDİ ALİ ULVİ (2015). Protective Effects of

Colchicine in an Experimental Rat Endometriosis Model Histopathological Evaluation and

Assessment of TNF Levels. Reproductive Sciences, 22(2), 258-263., Doi:

10.1177/1933719114542029 (Yayın No: 2451342)

8. KESKİN KURT RAZİYE,GÜLER OKYAY AYŞE,BENK ŞİLFELER DİLEK,karateke atilla,HAKVERDİ ALİ ULVİ

(2015). Relation of inflammatory markers with both presence and severity of hyperemesis

gravidarum. Ginekol Pol. 2014 Aug;85(8):589-93., 85(8), 589-593. (Yayın No: 2436981)

9. KESKİN KURT RAZİYE, KAYA ÖZLEM AYCAN, KARATEKE ATİLLA, BENK ŞİLFELER DİLEK, SOYLU

KARAPINAR OYA, AKKOCA AYŞE NESLİN, HAKVERDİ ALİ ULVİ (2014). Increased Density of demodex

folliculorum Mites in Pregnancies with Gestational Diabetes. Medical Principles and Practice, 23(4),

369-372., Doi: 10.1159/000363244 (Yayın No: 2437256)

10. BENK ŞİLFELER DİLEK, GÜNGÖREN ARİF, DOLAPÇIOĞLU KENAN SERDAR, KESKİN KURT RAZİYE,

KARATEKE ATİLLA, HAKVERDİ ALİ ULVİ, Gunher Arica Secil, BALOĞLU ALİ (2014). Mean Platelet

Volume Levels in Pregnant Women having Thalassemia Minors. International Journal of Basic and

Clinical Studies (IJBCS), 3(2), 44-49. (Yayın No: 8392939)

11. HAKVERDİ SİBEL, DEMİRHAN OSMAN, tunç erdal, İNANDIKOĞLU NİHAL, USLU İNAYET NUR,

GÜNGÖREN ARİF, ERDEM DUYGU, HAKVERDİ ALİ ULVİ (2013). Chromosome imbalances and

alterations in the p53 gene in uterine myomas from the same family members familial

leiomyomatosis in Turkey. Asian Pac J Cancer Prev. (Yayın No: 2451413)

12. HAKVERDİ SİBEL,GÜZELMANSUR İSMAİL,GÜNGÖREN ARİF,TOPRAK SERHAT,YALDIZ

MEHMET,HAKVERDİ ALİ ULVİ (2012). Evaluation of fetal autopsy findings in the hatay region 274

cases. Turkish Journal of Pathology, 28(2), 154, Doi: 10.5146/tjpath.2012.01115 (Yayın No:

13. HAKVERDİ SİBEL,GÜNGÖREN ARİF,YALDIZ MEHMET,HAKVERDİ ALİ ULVİ,TOPRAK SERHAT (2011).

Immunohistochemical analysis of p16 expression in uterine smooth muscle tumors. Eur J Gynaecol

Oncol. 2011;32(5):513-5. (Yayın No: 2451505)

14. GÜNGÖREN ARİF, DOLAPÇIOĞLU KENAN SERDAR, HAKVERDİ ALİ ULVİ, YETİM ÇAĞCIL (2011).

Uterin Kaviteyi Değerlendirmede,

TV-USG, SİS ve Histeroskopi

Ne Kadar Etkili?. Turkiye Klinikleri J Gynecol Obst, 21(1), 13-17. (Yayın No: 8392914)

4

Uluslararası hakemli dergilerde yayımlanan makaleler:

GÜNGÖREN ARİF, DOLAPÇIOĞLU KENAN SERDAR, HAKVERDİ ALİ ULVİ, YETİM ÇAĞCIL (2011).

Uterin Kaviteyi Değerlendirmede,

TV-USG, SİS ve Histeroskopi

Ne Kadar Etkili?. Turkiye Klinikleri J Gynecol Obst, 21(1), 13-17. (Yayın No: 8392914)

15. GÜNGÖREN ARİF, DOLAPÇIOĞLU KENAN SERDAR, HAKVERDİ ALİ ULVİ, YETİM ÇAĞCIL (2011).

Effectiveness of Periurethral Injection on Stress Urinary Incontinence. Turkiye Klinikleri Journal of

Medical Sciences, 31(4), 919-922., Doi: 10.5336/medsci.2010-18067 (Yayın No: 3384815)

16. HAKVERDİ SİBEL, GÜNGÖREN ARİF, HAKVERDİ ALİ ULVİ, DOLAPÇIOĞLU KENAN SERDAR, YALDIZ

MEHMET, BAYRAMOĞLU TEPE NESLİHAN (2011). Malignant Sarcomatous Mural Nodule Associated

with Ovarian Serous Cystadenoma: Case Report and Review of Literature. Turkiye Klinikleri J

Gynecol Obst, 21(1), 66-70. (Yayın No: 8392252)

17. HAKVERDİ SİBEL,DOLAPÇIOĞLU KENAN SERDAR,GÜNGÖREN ARİF,YALDIZ MEHMET,HAKVERDİ ALİ

ULVİ (2009). Multiple uterine angioleiomyomas mimicking an ovarian neoplasm a case report.

Eur J Gynaecol Oncol. 2009;30(5):592-4. (Yayın No: 2451524)

18. AYHAN ALİ,DURSUN POLAT,KUŞÇU ÜLKÜ ESRA,MÜLAYİM BARIŞ,HABERAL REYHAN ASUMAN

NİHAN,ÖZEN ÖZLEM,KÖSE M FARUK,TURAN AHMET TANER,ÖZGÜL NEJAT,DEMİR Ö

FARUK,ÇAVUŞOĞLU H DENİZ,YÜCE KUNTER,KUZEY MOCAN GAMZE,SALMAN MEHMET

COŞKUN,VELİPAŞAOĞLU MELİH,YENEN MÜFİT CEMAL,DEDE MURAT,ONAN MEHMET ANIL,GÜNER

HALDUN,TAŞKIRAN ÇAĞATAY,ERDEM ÖZLEM,SARAÇOĞLU FERİT,SERİN İBRAHİM SERDAR,ÖZÇELİK

BÜLENT,SOYER IŞIN,GÜZİN KADİR,DOĞANYILMAZ SONER,KARA OSMAN FADIL,KIRAN

GÜRKAN,METİNDİR JALE,OZAN HAKAN,ÖZALP SİNAN,VARDAR MEHMET ALİ,ZEREN EMİNE

HANDAN,DİLEK SAFFET,BOZKAYA HASAN,GÜVEN SÜLEYMAN,ERSÖZ ŞAFAK,AÇIKALIN

ARBİL,MEYDANLI MEHMET MUTLU,ÇETİNARSLAN İLKNUR,GÖKASLAN HÜSNÜ,EREN ŞİRİN

FUNDA,ÇELİK ÇETİN,YILMAZ OSMAN,ÇELİK HÜSNÜ,AKSAZ ZELİHA,KOÇAK CENGİZ,BAĞCI

HAFİZE,DAVUTOĞLU BİLGE,HAKVERDİ ALİ ULVİ,SOYSAL MEHMET EMİN,KAYA GÜLCAN,YANIK

ALİ,ARICI DİLEK SEMA,ÇETİN HALİT,MUTLU AHMET EMİN,KOLUSARI ALİ,KÖSEM MUSTAFA,ŞAHİN

HANIM GÜLER,DEMİRTÜRK FAZLI,GÜLTEKİN MURAT,KARACA MEHMET,HARMA MEHMET

İBRAHİM,HARMA MÜGE,BATUR ŞEBNEM,DEMİRBAĞ NİLGÜN,BAYKAL CEM MURAT,DOĞAN EKİCİ

ASİYE IŞIN,DEMİR ŞAM ASLI (2009). Prevalence of cervical cytological abnormalities in Turkey.

International Journal of Gynecology Obstetrics, 106(3), 206-209., Doi: 10.1016/j.ijgo.2009.04.003

19. ÇETİN MERYEM,OCAK SABAHATTİN,GÜNGÖREN ARİF,HAKVERDİ ALİ ULVİ (2007). Distribution of

Candida species in women with vulvovaginal symptoms and their association with different ages

and contraceptive methods. Scandinavian Journal of Infectious Diseases, 39(6-7), 584-588., Doi:

10.1080/00365540601148491 (Yayın No: 2451616)

20. OCAK SABAHATTİN,ÇETİN MERYEM,HAKVERDİ SİBEL,DOLAPÇIOĞLU KENAN SERDAR,GÜNGÖREN

ARİF,HAKVERDİ ALİ ULVİ (2007). Effects of intrauterine device and oral contraceptive on vaginal

flora and epithelium. Saudi Med J. (Yayın No: 2451643)

21. YALDIZ MEHMET,HAKVERDİ ALİ ULVİ,BAYHAN GÖKHAN,AKKUŞ Z (2005). Expression of E cadherin

in squamous cell carcinomas of the cervix with correlations to clinicopathological features. Eur J

Gynaecol Oncol. 2005;26(1):95-8. (Yayın No: 2451727)

22. HAKVERDİ ALİ ULVİ,GÜL TALİP,TANER CÜNEYİT EFTAL,VURAL ATİYE,ERDEN ALİ

CEYLAN,YILMAZTÜRK A (1997). Treatment of chronic cervicitis the loop electrosurgical excision

procedure. Zentralblatt Gynakologi (Yayın No: 2451852)

23. AYHAN A,TUNCER ZAFER SELÇUK,HAKVERDİ ALİ ULVİ,YÜCE KUNTER (1996). Sertoli Leydig cell

tumor of the ovary a clinicopathologic study of 10 cases. Eur J Gynaecol Oncol. 1996;17(1):75-8.

(Yayın No: 2452018)

24. TANER CÜNEYİT EFTAL,HAKVERDİ ALİ ULVİ,ABAN ÜMMÜHAN MERAL,ERDEN ALİ

CEYLAN,ÖZELBAYKAL U (1996). Prevalence management and outcome in eclampsia. Int J

Gynaecol Obstet. 1996 Apr;53(1):11-5. (Yayın No: 2451971)

25. TANER CÜNEYT EFTAL, HAKVERDİ ALİ ULVİ, ABAN ÜMMÜHAN MERAL (1996). Emergency cesarean

hysterectomy

. Medikal Network, 2, 96-100. (Yayın No: 8397778)

26. YAYLA MURAT, HAKVERDİ ALİ ULVİ, BİLİCİ ASLAN, ÖZELBAYKAL UFUK, ERDEN CEYLAN (1996).

Previous poor obstetrical history:is it associated with abnormal umblical artery doppler findings

in a subsequent pregnancy?

. Gynecology, Obstetrics& Reproductive Medicine, 2(1), 181-185. (Yayın No: 8393148)

27. HAKVERDİ ALİ ULVİ,TANER CÜNEYİT EFTAL,ABAN ÜMMÜHAN MERAL,VURAL ATİYE,GÜNGÖREN

ARİF,YILMAZ NAFİ (1996). Incomplete androgen insensitivity testicular feminization syndrome

two case reports. Acta Obstetricia et Gynecologica Scandinavica, 75(6), 588-592., Doi:

10.3109/00016349609054677 (Yayın No: 2451904)

28. TANER CÜNEYİT EFTAL,HAKVERDİ ALİ ULVİ,ERDEN ALİ CEYLAN,SATICI OMER (1995). Menstrual

disorders and pelvic pain after sterilization. Adv Contracept. 1995 Dec;11(4):309-15. (Yayın No:

2452083)

5

Uluslararası hakemli dergilerde yayımlanan makaleler:

29. HAKVERDİ ALİ ULVİ,TANER CÜNEYİT EFTAL,ERDEN ALİ CEYLAN,SATICI ÖMER (1994). Changes in

ovarian function after tubal sterilization. Adv Contracept. 1994 Mar;10(1):51-6. (Yayın No:

2452120)

30. TANER CÜNEYİT EFTAL,HAKVERDİ ALİ ULVİ (1993). Hygroscopic cervical dilators in eclampsia. Int J

Gynaecol Obstet. 1993 Jun;41(3):283-4. (Yayın No: 2452142)

31. TANER CÜNEYT EFTAL, YILMAZTÜRK ahmet, HAKVERDİ ALİ ULVİ (1993). Inversio uteri puerperalis:

Eine gefährliche komplikation der nachgeburtsperiode.

. TW Gynäkologie, 6, 62-67. (Yayın No: 8397023)

PROF. DR. ALİ ULVİ HAKVERDİ

GÖREV ALDIĞI BÖLÜMLER

KADIN HASTALIKLARI VE DOĞUM

THE EFFECT OF PREGNANCY ON URINARY SYMPTOMS

By

Beyazit, A (Beyazit, Ahmet) [1] ; Hakverdi, AU (Hakverdi, Ali Ulvi) [1] ; Goezuekara, KH (Goezuekara, Kerem Han) [2]

 (provided by Clarivate) 

Source

CUREUS JOURNAL OF MEDICAL SCIENCE

Volume

15

Issue

8

DOI

10.7759/cureus.44232

Article Number

e44232

Published

AUG 28 2023

Indexed

2023-09-25

Document Type

Article

Abstract

BackgroundUrinary incontinence is a condition that causes social, medical, or hygienic problems. The increase in the incidence of stress incontinence, particularly with increasing parity, emphasizes the role of pregnancy on the etiology of incontinence and other urinary symptoms. This study aimed to estimate the effect of pregnancy on urinary incontinence and other urinary symptoms with history and urodynamic data.MethodologyThis study was conducted at Mustafa Kemal University, Medical Faculty, Obstetrics and Gynecology Department. A total of 72 pregnant primigravid women without any urinary problems were included in the study. Patients with severe chronic disease, neurological disorders, antepartum hemorrhage, multiple pregnancies, younger than 18, and those with physical and mental disabilities were excluded. All patients were initially evaluated in the first trimester and finally in the sixth week of the postpartum period. Demographic and obstetric data, including urological complaints and urodynamic findings, were recorded.ResultsThere were significant increases in nocturia, frequency, dysuria, urgency, and stress urinary incontinence complaints in pregnant women. Urge incontinence was not significantly different after pregnancy. In the postpartum urodynamic studies, nine (12.5%) patients with stress urinary incontinence and six (8.3%) patients with detrusor instability were detected. There was no significant difference between cesarean section and vaginal delivery regarding incontinence.ConclusionsAccording to the study findings, pregnant women who were continent before pregnancy could become incontinent after birth according to urodynamic data. However, long-term studies are needed to determine whether this incontinence is temporary. Additionally, according to our results, cesarean section should not be recommended over vaginal delivery only to prevent incontinence.

Keywords

Author Keywords

urodynamicmode of deliverylower urinary tract symptomsurinary incontinencepregnancy
 

EFFECTIVENESS OF PERIURETHRAL INJECTION ON STRESS URINARY INCONTINENCE

By

Güngören, A (Gungoren, Arif) [1] ; Dolapçioglu, K (Dolapcioglu, Kenan) [1] ; Hakverdi, AU (Hakverdi, Ali Ulvi) [1] ; Yetim, Ç (Yetim, Cagcil) [1]

 (provided by Clarivate) 

Source

TURKIYE KLINIKLERI TIP BILIMLERI DERGISI

Volume

31

Issue

4

Page

919-922

DOI

10.5336/medsci.2010-18067

Published

AUG 2011

Indexed

2011-11-09

Document Type

Article

Abstract

Objective: To determine one-year subjective and objective evaluation results of penurethral injection (PUT) applied to women suffering from stress urinary incontinence (SUI). Material and Methods: Twenty five patients with complaints of SUI have participated in our study. Preoperative and postoperative results of urinalysis, stress and Q-tip tests, post voiding residual volumes (RV) and survey of incontinence quality of life (I-QOL) criteria were recorded. Later on, Urodex (R) (Cross- linked hyaluronic acid, detxranomere) was injected to them. The cases were monitored at regular intervals for a mean of 14 +/- 5.84 months. Results: Eighteen (72%) out of all cases were encountered during menopausal period. Eight of the patients had previous gynecologic operations. Mean age was 53.97 +/- 13.01 years. Mean application period of PUT was 6.95 +/- 1.46 minutes. Differences between the preoperative and postoperative results of RV and I-QOL were not statistically significant. From subjective success point of view; 17 (68%) of the patients claimed no change on their incontinence problem, two (8%) of the patients claimed that their conditions were slightly improved, and six (24%) of the patients claimed that their conditions significantly improved. When objective success is considered, there was success in seven (28%) patients, and failure in 18 (72%) patients. Conclusion: PUT is a minimally invasive treatment method used in all types of SUI. PUI treatment might be preferred for the old, obese patients with additional health problems, having incontinence dependent on hypermobility at which the open surgery incurs a great risk. However, as the new techniques are not readily available, a periurethral injection technique may still be a valid choice in patients who have poor surgical risks, and to whom the low success rate has been adequately explained.

Keywords

Author Keywords

Urinary incontinencestressurinary bladder neck obstruction
 

Keywords Plus

TRANSURETHRAL COLLAGEN INJECTIONQUALITY-OF-LIFEFOLLOW-UPWOMENTHERAPYSYSTEM

The Investigation of the Association Between the Frequency of Trichomonas Vaginalis and Using Intrauterine Contraceptive Device

By

Duran, N (Duran, Nizami) [1] ; Çulha, G (Culha, Guelnaz) [2] ; Hakverdi, AU (Hakverdi, Ali Ulvi) [3] ; Güngören, A (Gungoren, Arif) [3]

 (provided by Clarivate) 

Source

TRAKYA UNIVERSITESI TIP FAKULTESI DERGISI

Volume

26

Issue

3

Page

197-202

Published

SEP 2009

Indexed

2009-09-01

Document Type

Article; Proceedings Paper

Conference

Meeting

12th International Congress of Bacteriology and Applied Microbiology

Location

Istanbul, TURKEY

Date

AUG 05-09, 2008

Abstract

Objectives: We investigated the association between the frequency of Trichomonas vaginalis and using intrauterine contraceptive device (IUD).

Patients and Methods: A total of 1058 vaginal swab samples were collected. The study population included 402 symptomatic and 656 asymptomatic women, between 18-45 years of age. Specimens were taken with a speculum and sterile cotton swabs from the posterior fornix of the vagina. Wet mount preparations were examined first, and then inoculated into Trypticase-yeast extract-maltose medium.

Results: T vaginalis was determined in 35 (3.31%) samples out of 1058 specimens using both diagnostic methods (direct examination and/or culture). While a total of 402 women were symptomatic, 656 women were asymptomatic. Among 190 IUD users, the frequency of T vaginalis was determined as 6.84%, and among 868 non-users, this ratio was determined as 2.53%. Moreover, while among 100 symptomatic women with IUD, 11 women were positive for T vaginalis (11%), of the 302 symptomatic women without IUD, 17 were positive (5.63%) for T vaginalis. Significant correlation was determined between the use of IUD and the presence of T vaginalis (p<0.05).

Conclusion: These results showed that IUD use may increase the growth of T vaginalis in the vaginal mucosa. To reduce the incidence of this pathogen in IUD users, they should be followed up closely.

Keywords

Author Keywords

Trichomonas vaginalisintrauterine contraceptive devicevaginal infectionsymptomatic infectionasymptomatic infection
 

Investigation of the prevalence of Trichomonas vaginalis in women with complaints of vaginal discharge and itching

Vaginal Akinti ve Kasinti Sikayeti Olan Kadinlarda Trichomonas vaginalis Yayginliginin Arastirilmasi

By

Culha, Gulnaz; Hakverdi, Ali Ulvi; Zeteroglu, Sahin; Duran, Nizam

 (provided by Clarivate) 

Source

Turkiye Parazitoloji Dergisi

Volume

30

Issue

1

Page

16-8

Published

2006

Indexed

2006-01-01

Document Type

English Abstract; Journal Article

Abstract

Trichomonas vaginalis (T vaginalis) is the most common pathogen that is sexually spread in women. In this study, the presence of Trichomonas vaginalis was investigated in patients with vaginal discharge and itching who presented at the polyclinic of the Mustafa Kemal University Medical Faculty Department of Gynecology. These women were between 20-40 years of age. During gynecologic examination of patients, vaginal fluid samples were collected with swaps from the speculum and fornics to two tubes that contained sterile saline. One of the vaginal discharges collected with swaps was used for direct microscopic examination and Giemsa staining. The other one was used for culturing for T vaginalis in Trichomonas medium that contained horse serum and antibiotics. While the frequency of T vaginalis was found to be 1.81% (5 of the 275 samples) by the direct microscopic examination and Giemsa stain, this ratio was 2.18% (6 of the 275 samples) by the culture method. In conclusion, it was decided to use the culture method in diagnosis of T vaginalis in addition to direct microscopic examination. This was the first study of T vaginalis infection in our region and it was compared with other studies carried out in other regions of Turkey. Our results were somewhat lower than those in other regions.

DEEP VEIN THROMBOSIS IN PREGNANT WOMEN WITH HETEROZYGOUS FACTOR-V LEIDEN MUTATION: A CASE REPORT

By

Fansa, I (Fansa, Iyad) [1] ; Güngören, A (Gungoren, Arif) [2] ; Hakverdi, AU (Hakverdi, Ali Ulvi) [2] ; Zeteroglu, S (Zeteroglu, Sahin) [2] ; Yetim, Ç (Yetim, Cagcil) [2]

Source

TURK GOGUS KALP DAMAR CERRAHISI DERGISI-TURKISH JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Volume

17

Issue

3

Page

208-209

Published

JUL 2009

Indexed

2009-07-01

Document Type

Article

Abstract

Deep vein thrombosis during pregnancy is an important risk factor increasing maternal morbidity and mortality. Factor V Leiden mutation is the most frequent one among many hereditary and acquired thrombophilic risk factors during pregnancy. In a 23-year-old woman who had been pregnant for 11 weeks and applied to hospital with sudden onset pain, swelling, and erythema in her left lower extremity, a thrombus from left main iliac to superficial femoral veins was detected via Doppler ultrasonography. She was hospitalized and low molecular-weight heparin (enoxaprine sodium) was initiated with a dosage of 12000 IU/day. She showed a rapid healing clinically and was followed up with enoxaprine and varsity sock until delivery. After labor, the dosage of enoxaprine was halved and withdrawn after six weeks, and oral warfarin sodium was started. The patient is still continued to be followed up without any problems.

Keywords

Author Keywords

Deep vein thrombosisenoxaprinefactor V Leiden mutationpregnancy
 

Keywords Plus

PUERPERIUM

Twin pregnancy with a complete hydatidiform mole and co-existent live fetus: two case reports and review of the literature

By

Dolapcioglu, K (Dolapcioglu, Kenan) [1] ; Gungoren, A (Gungoren, Arif) [1] ; Hakverdi, S (Hakverdi, Sibel) [2] ; Hakverdi, AU (Hakverdi, Ali Ulvi) [1] ; Egilmez, E (Egilmez, Ertugrul) [3]

 (provided by Clarivate) 

Source

ARCHIVES OF GYNECOLOGY AND OBSTETRICS

Volume

279

Issue

3

Page

431-436

DOI

10.1007/s00404-008-0737-x

Published

MAR 2009

Indexed

2009-03-01

Document Type

Article

Abstract

The aim of this study was to report the clinical features, management, and outcome of two cases of complete hydatidiform mole with a coexisting viable fetus and to review the literature.

In this article, we report on the well-documented follow-up of two cases of twin pregnancies with complete hydatidiform mole and a normal fetus. Genetic amniocentesis showed normal fetal karyotype in both of two cases. In the first case, a live male infant was delivered by a cesarean section because of severe maternal bleeding at 29 weeks of gestation. In the second case, termination of pregnancy was performed due to early onset of severe preeclampsia and vaginal hemorrhage.

The chances of a live birth have been estimated between 30 and 35% and the risk of persistent trophoblastic disease is similar to singleton molar pregnancies in complete mole with coexisting fetus pregnancy. Therefore, in these pregnancies, expectant management instead of termination of pregnancy can be suggested.

Keywords

Author Keywords

Gestational trophoblastic diseaseHydatidiform moleTwin pregnancy
 

MUCINOUS CYSTADENOMATOGETHER WITH ENDOMETRIOMA: CASE REPORT

By

Güngören, A (Gungoren, Arif) [1] ; Kakverdi, S (Kakverdi, Sibel) [2] ; Hakverdi, AU (Hakverdi, Ali Ulvi) [1] ; Karazincir, S (Karazincir, Sinem) [3] ; Karapinar, S (Karapinar, Soylu) [1]

 (provided by Clarivate) 

Source

TURKISH JOURNAL OF OBSTETRICS AND GYNECOLOGY

Volume

5

Issue

1

Page

29-31

Special Issue

SI

Published

JUN 2008

Indexed

2008-06-01

Document Type

Article

Abstract

Endometriosis effects 2-5 % of women at reproductive age. Malignant transformation of endometrioma is around 2.5 %. Ovarian mucinous tumors constitute approximately 10 % of all ovarian neoplasms.

35-year-old woman with gravida 0 parite 0, admitted with pelvic pain for two days, to our hospital. She had laparoscopic surgery for right ovarian cyst nine years ago, the pathological examination of which was endometrioma. Gynecological examination of patient revealed semisolid masses about 6 cm in diameter in bilateral ovaries. CA-125 and CA-19,9 were found 121.5mIU/L, 127.3mIU/L, respectively other tumor markers were within normal levels. After her approval bilateral ovarian cyst excision with laparotomy was carried out. Pathological examination demonstrated mucinous cystadenoma in the right ovary and endometrioma in the left ovary. Ovarian ephitelial malign tumors can be found together with endometrioma. Epithelial metaplastic transformation, especially ciliated cell and eosinophilic transformation were often reported, whereas hobnail and mucinous transformation were reported rarely in ovarian endometriosis. Mucinous metaplasia and hyperplasia in ovarian endometriosis might be closely associated with the development of mucinous borderline tumors. We didn't find mucinous cystadenoma reported together with endometrioma in literature.

Keywords

Author Keywords

Endometriomamucinous cystadenoma

DISTRIBUTION OF CANDIDA SPECIES IN WOMEN WITH VULVOVAGINAL SYMPTOMS AND THEIR ASSOCIATION WITH DIFFERENT AGES AND CONTRACEPTIVE METHODS

By

Cetin, M (Cetin, Meryem) ; Ocak, S (Ocak, Sabahattin) ; Gungoren, A (Gungoren, Arif) ; Hakverd, AU (Hakverd, Ali Ulvi)

Source

SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES

Volume

39

Issue

6-7

Page

584-588

DOI

10.1080/00365540601148491

Published

2007

Indexed

2007-01-01

Document Type

Article

Abstract

The aim of this study was to determine the frequency and distribution of Candida spp. within different age groups and different contraceptive methods users in women with vulvovaginal symptoms. The study included 569 female outpatients who had visited the Education and Research Hospital of Mustafa Kemal University, Turkey, between Jaunary 2004 and June 2005. Among 569 women with symptoms of vulvovaginitis, 240 (42.2%) were positive for Candida spp., of which 106 (44.2%) were C. albicans and 134 (55.8%) were non-albicans spp. The age group 26-30 y had the highest frequency of Candida spp. (23.7%). Candida spp. were isolated from 44.2% of contraceptive method users, and 37.9% of noncontraceptive users (p > 0.05). The isolation rate of C. albicans was higher among oral-contraceptive users (57.5%) than IUCD users (38.5%), coitus interruptus (48.5%) and condom users (42.8%). These results indicate that factors associated with age and contraceptive method used may influence the occurrence and distribution of Candida spp. in women with vulvovaginal symptoms.

Keywords

Keywords Plus

VAGINITISSUSCEPTIBILITYINFECTIONSPREVALENCEGLABRATATRACT

DETECTION OF TRICHOMONAS VAGINALIS IN VAGINAL SPECIEMENS FROM WOMEN BY WET MOUNT, CULTURE AND PCR

By

Çulha, G (Culha, Gulnaz) [1] ; Gungoren, A (Gungoren, Arif) [3] ; Demir, C (Demir, Cemil) [4] ; Hakverdi, AU (Hakverdi, Ali Ulvi) [3] ; Duran, N (Duran, Nizami) [2]

 (provided by Clarivate) 

Source

JOURNAL OF CLINICAL AND ANALYTICAL MEDICINE

Volume

6

Issue

5

Page

537-540

DOI

10.4328/JCAM.2158

Published

SEP 2015

Indexed

2016-06-15

Document Type

Article

Abstract

Aim: Trichomoniasis, a sexually transmitted infection (STI) caused by Trichomonas vaginalis, affects 180 million people worldwide and causes significant morbidity. Infection with T. vaginalis has been associated with vaginitis, exocervicitis, and urethritis in women. Material and Method: In this study, we aim to investigate the presence of T. vaginalis by using three different methods for comparing the results. Two hundred T. vaginalis isolates taken from swap samples were collected in Medical Faculty, Department of Gynecology, Mustafa Kemal University Polyclinic, and examined genotypically and phenotypically to identify T. vaginalis in Parasitology Department. This research is unique in terms of its contribution to patient treatment, being the first molecular study in Turkey/Hatay to determine Trichomonas (TV) genes stemming from Trichomonas vaginalis strains.R esult: 56 out of 200 patients examined were identified as positive and 24 (42.8%) of these were identified through microscopy, 18 (32,1%) with culture and 24 (42,8%) with PCR. The number of those identified through all these methods is 14 (25%). In this study, difference was calculated using three methods (p=0.022) with Cochran's Q test. When compared with McNemar two by two, no superiority in T. vaginalis diagnosis was found between microscopy and culture (p=0.5), microscopy and PCR (p=0.063), or culture and PCR (p=0.25) methods. Discussion: Culture method is not used in routine laboratory procedures and has contamination risk. PCR method shows directly the parasite of DNAs, and so it is thought to be more reliable compared to the other two methods.

Keywords

Author Keywords

Trichomonas VaginalisMicroscopyCulturePCR
 

Keywords Plus

POLYMERASE-CHAIN-REACTIONSEXUALLY-TRANSMITTED-DISEASESPREGNANT-WOMENDIAGNOSISINFECTIONMICROSCOPYSPECIMENSASSAYDNA

Evaluation of Fetal Autopsy Findings in the Hatay Region: 274 Cases

By

Hakverdi, S (Hakverdi, Sibel) [1] ; Güzelmansur, I (Guzelmansur, Ismail) [3] ; Güngören, A (Gungoren, Arif) [2] ; Toprak, S (Toprak, Serhat) [1] ; Yaldiz, M (Yaldiz, Mehmet) [1] ; Hakverdi, AU (Hakverdi, Ali Ulvi) [3]

 (provided by Clarivate) 

Source

TURKISH JOURNAL OF PATHOLOGY

Volume

28

Issue

2

Page

154-161

DOI

10.5146/tjpath.2012.01115

Published

2012

Indexed

2012-01-01

Document Type

Article

Abstract

Objective: The aim of this study was to present the incidence of fetal anomalies in our region of Hatay, Turkey in order to determine the efficiency of prenatal diagnosis through fetal autopsy, and to compare our statistical data with other national and international studies.

Material and Method: This study was conducted on 274 fetuses from terminated pregnancies due to abnormal prenatal findings and intrauterine deaths from 2005 to September 2010. Fetuses were evaluated through postmortem examination, external measurements, X-rays, Magnetic Resonance Images, Multislice Computerized Tomography and photographs. The autopsy was completed by the histological examination of each organ.

Results: Autopsy was conducted on 274 fetuses. A fetal anomaly was detected in 160 (58.39%) cases. The central nervous system contained the most frequent structural defects (79 cases, 49.38%), followed by malformations in the musculoskeletal system in 36 cases (22.5%). The most frequent multiple system anomalies were central nervous system defect and bilateral adrenal agenesis, musculoskeletal system malformations and urinary system defects. Fetal autopsy provided additional findings in 43 cases (26.88%).

Conclusion: Fetal autopsy is a very important procedure and an integral part of the general prenatal management. New findings through this method may suggest invaluable data for parents about potential risks in future pregnancies.

Keywords

Author Keywords

AutopsyFetal diseasesPrenatal diagnosisHatay

DIAGNOSTIC VALUE OF DILATATION AND CURETTAGE TO DETECT INTRAUTERINE LESIONS IN WOMEN WITH ABNORMAL UTERINE BLEEDING

By

Hakverdi, S (Hakverdi, Sibel) [1] ; Güngören, A (Gungoren, Arif) [2] ; Hakverdi, AU (Hakverdi, Ali Ulvi) [2] ; Dolapçioglu, K (Dolapcioglu, Kenan) [3] ; Çiftçi, S (Ciftci, Sinasi) [2] ; Kaya, Z (Kaya, Zozan) [4] ; Yalinkaya, A (Yalinkaya, Ahmet) [4]

 (provided by Clarivate) 

Source

TURKISH JOURNAL OF OBSTETRICS AND GYNECOLOGY

Volume

5

Issue

3

Page

202-206

Published

SEP 2008

Indexed

2008-09-01

Document Type

Article

Abstract

Objective: To evaluate the diagnostic inadequacy of dilatation and curettage (D&C) by comparing histologic findings derived from D&C with histologic findings obtained after hysterectomy procedure retrospectively.

Material and methods: Files of 259 patients with abnormal uterine bleeding who underwent hysterectomy within two months of a diagnostic D&C were analyzed. All patients had gynecologic and ultrasonographic examination, then they underwent D&C procedure under anesthesia. Hysterectomy was performed accordingly due to the histologic findings or persistence of the symptoms. Histologic diagnosis in D&C and after hysterectomy for each patient were compared.

Results: 54.5% of the women had no pathology in D&C techniques. 59.5% of remaining patients had the same the pathologic findings in the hysterectomy specimens. In 105 of 259 patients, D&C failed to detect intrauterine disorders subsequently found at hysterectomy. After hysterectomy, in 227 of 259 patients were found additional pathologic abnormalities besides the histologic diagnosis in D&C specimens.

Conclusions: D&C involves additional hospital costs and risk of complications; uterine perforation, infection and laceration of the cervix. If there are lesions in the uterus, dilatation and curettage is an inadequate diagnostic tool. D&C missed 40.5% of major intrauterine disorders and endometrial lesions were still present in the removed uterus. Therefore D&C can not be assessed as a therapeutic tool. Therefore D&C is suggested to be replaced by alternative and more accurate methods of diagnosis of endometrial abnormalities.

Keywords

Author Keywords

dilatation and curettageendometrial pathologyhysterectomy

DOES THE PRESENCE OF ANHYDRAMNIOS AFFECT THE DURATION OF MEDICAL ABORTION?

By

Karapinar, OS (Karapinar, Oya Soylu) [1] ; Güngören, A (Gungoren, Arif) [1] ; Dolapçioglu, K (Dolapcioglu, Kenan) [1] ; Silfeler, DB (Silfeler, Dilek Benk) [1] ; Kurt, RK (Kurt, Raziye Keskin) [1] ; Sahin, H (Sahin, Hanifi) [1] ; Hakverdi, AU (Hakverdi, Ali Ulvi) [1]

 (provided by Clarivate) 

Source

GINEKOLOGIA POLSKA

Volume

87

Issue

9

Page

635-638

DOI

10.5603/GP.2016.0058

Published

2016

Indexed

2016-11-16

Document Type

Article

Abstract

Objectives: The aim of the study was to determine whether anhydramnios affected the duration of medical abortion in cases with various indications as compared to cases with normal amniotic fluid volume.

Material and methods: Patients who were admitted to our clinic because of medical abortion between January 2010-December 2013 were included in this retrospective study. A total of 32 pregnant women with anhydramnios (study group) and 67 pregnant women with normal amniotic fluid volume but with fetal abnormality (control group) were included in the study. Patient age, gravidity, parity, gestational age, previous delivery route, and duration of the abortion were recorded.

Results: Mean duration of the abortion in the study group was 71.93 +/- 47.51 h as compared to 79.08 +/- 52.62 h in the control group. There were no statistically significant differences between the two groups in terms of duration of the abortion (p = 0.516). Also, we found no statistically significant differences in duration of the abortion with regard to previous delivery route (p = 0.220).

Conclusions: There were no statistically significant differences between the study group and controls in terms of duration of the abortion. In addition, neither parity nor previous delivery route affected the duration of the abortion.

Keywords

Author Keywords

medical abortionanhydramniosduration of abortus
 

Keywords Plus

2ND-TRIMESTER PREGNANCY TERMINATION3RD TRIMESTER PREGNANCIESINTRAVAGINAL MISOPROSTOLVAGINAL MISOPROSTOLCESAREAN DELIVERY2ND TRIMESTERWOMENINDUCTIONMIFEPRISTONESECTION

The effect of obesity on inflammatory markers in patients with PCOS: a BMI-matched case-control study

By

Kurt, RK (Kurt, Raziye Keskin) [1] ; Okyay, AG (Okyay, Ayse Guler) [1] ; Hakverdi, AU (Hakverdi, Ali Ulvi) [1] ; Gungoren, A (Gungoren, Arif) [1] ; Dolapcioglu, KS (Dolapcioglu, Kenan Serdar) [1] ; Karateke, A (Karateke, Atilla) [1] ; Dogan, MO (Dogan, Mustafa Ozcil) [1]

 (provided by Clarivate) 

Source

ARCHIVES OF GYNECOLOGY AND OBSTETRICS

Volume

290

Issue

2

Page

315-319

DOI

10.1007/s00404-014-3199-3

Published

AUG 2014

Indexed

2014-08-27

Document Type

Article

Abstract

Previous studies have shown increased inflammatory activity in patients with polycystic ovary syndrome (PCOS); however, it remains uncertain whether this increased inflammatory activity is a consequence of the disorder itself or of the accompanying obesity. We therefore aimed to test the inflammatory marker levels in obese and lean patients with PCOS by using two separate control groups with matching body mass index (BMI).

A total of 120 women in reproductive age with (n = 62) and without (n = 60) PCOS were recruited for the study. Patients with PCOS were divided into two groups as obese (n = 32) and lean (n = 30) PCOS groups according to BMI. Two BMI-matched control groups were created. Furthermore, high sensitive CRP protein (hsCRP), neutrophils, lymphocytes, white blood cell count (WBC) and neutrophil to lymphocyte ratio (NLR) were evaluated with complete blood count.

The hsCRP (5.5 +/- A 0.8 vs. 3.1 +/- A 0.7, p < 0.001), neutrophil count (3.8 +/- A 0.4 vs. 2.9 +/- A 0.7, p < 0.001), leukocyte count (7.2 +/- A 1.8 vs. 5.6 +/- A 1.6, p < 0.001), and NLR (2.6 +/- A 1.4 vs. 1.5 +/- A 0.4, p < 0.001) were higher in patients with PCOS compared to the control group while lymphocyte count was lower (1.71 +/- A 0.65 vs. 1.98 +/- A 0.39, p = 0.008). Similarly, both obese and lean patients with PCOS had higher levels of hsCRP, neutrophils, leukocytes and NLR ratios compared to BMI-matched controls. The correlation analysis revealed a moderate correlation between NLR and hsCRP (r 0.459, p < 0.001), and between HOMA-IR (r 0.476 p < 0.001) and BMI (r 0.310, p 0.001).

Our study results demonstrated that both lean and obese patients with PCOS have increased inflammatory markers compared to BMI-matched control groups indicating that the inflammation seen in PCOS might be related with the presence of the disorder rather than with obesity.

Keywords

Author Keywords

Polycystic ovary syndromeNeutrophil lymphocyte ratioInflammationObesity
 

Keywords Plus

POLYCYSTIC-OVARY-SYNDROMEGRADE CHRONIC INFLAMMATIONNEUTROPHIL-LYMPHOCYTE RATIOC-REACTIVE PROTEINDIAGNOSTIC-CRITERIAWOMENDISEASECOUNT

PROTECTIVE EFFECTS OF COLCHICINE IN AN EXPERIMENTAL RAT ENDOMETRIOSIS MODEL: HISTOPATHOLOGICAL EVALUATION AND ASSESSMENT OF TNF-Α LEVELS

By

Kurt, RK (Kurt, Raziye Keskin) [1] ; Pinar, N (Pinar, Neslihan) [2] ; Karateke, A (Karateke, Atilla) [1] ; Okyay, AG (Okyay, Ayse Guler) [1] ; Silfeler, DB (Silfeler, Dilek Benk) [1] ; Albayrak, A (Albayrak, Aynur) [3] ; Özdemir, S (Ozdemir, Seyda) [4] ; Hakverdi, AU (Hakverdi, Ali Ulvi) [1]

 (provided by Clarivate) 

Source

REPRODUCTIVE SCIENCES

Volume

22

Issue

2

Page

258-263

DOI

10.1177/1933719114542029

Published

FEB 2015

Indexed

2015-02-25

Document Type

Article

Abstract

Objective: Endometriosis is an estrogen-dependent chronic inflammatory disease observed in reproductive period. The aim of the present study is to assess the efficacy of colchicine, widely used to treat many inflammatory diseases, in an experimental rat endometriosis model.

Study Design: Experimental endometriosis was constituted with implantation of autogenous endometrial tissue. Rats were divided randomly into 2 groups as colchicine group (n = 8) and control group (n =8). Although oral 0.1 mg/kg colchicine was administered 4 weeks to the colchicine group, the same amount of saline solution was administered to the control group. Before and after 30 days of treatment period, peritoneal and tissue tumor necrosis factor (TNF-), the volumes and histopathological properties of the implants were evaluated.

Results: Although the implant volume decreased significantly in the colchicine group (89.2 13.4 mm(3) to 35.2 +/- 4.5 mm(3), P < .05), the implant volume increased in the control group (85.1 +/- 14.2 mm3 to 110.3 +/- 10.5 mm(3), P < .05). When compared to the control group, the colchicine group had significantly lower histopathologic sores (1.4 +/- 0.2 vs 2.6 +/- 0.4, P < .001). Although peritoneal fluid TNF- levels were significantly decreased in the colchicine group (45.2 +/- 5.3 pg/mL vs 12.1 +/- 5.2 pg/mL, P < .001), the peritoneal fluid TNF- levels were significantly increased in the control group after the treatment (44.2 +/- 3.5 pg/mL vs 61.3 +/- 12.2 pg/mL; P < .001). Tissue TNF- levels were significantly lower in the colchicine group when compared to the control group (45.4 +/- 8.6 pg/mL vs 71.3 +/- 11.2 pg/mL; P < .001).

Conclusion: Colchicine resulted in regression of endometrial implant volumes in experimental rat endometriosis model and decreased peritoneal and tissue TNF- levels.

Keywords

Author Keywords endometriosisTNF-alphacolchicineinflammation
 

Keywords Plus

WOMENPATHOGENESISDIAGNOSISTISSUECELL

Chromosome Imbalances and Alterations in the p53 Gene in Uterine Myomas from the Same Family Members: Familial Leiomyomatosis in Turkey

By

Hakverdi, S (Hakverdi, Sibel) [1] ; Demirhan, O (Demirhan, Osman) [3] ; Tunc, E (Tunc, Erdal) [3] ; Inandiklioglu, N (Inandiklioglu, Nihal) [3] ; Uslu, IN (Uslu, Inayet Nur) [3] ; Gungoren, A (Gungoren, Arif) [2] ; Erdem, D (Erdem, Duygu) [2] ; Hakverdi, AU (Hakverdi, Ali Ulvi) [2]

 (provided by Clarivate) 

Source

ASIAN PACIFIC JOURNAL OF CANCER PREVENTION

Volume

14

Issue

2

Page

651-658

DOI

10.7314/APJCP.2013.14.2.651

Published

2013

Indexed

2013-11-07

Document Type

Article

Abstract

Uterine leiomyomas (UL) are extremely common neoplasms in women of reproductive age, and are associated with a variety of characteristic choromosomal aberrations (CAs). The p53 gene has been reported to play a crucial role in suppressing the growth of a variety of cancer cells. Therefore, the present study investigated the effects of CAs and the p53 gene on ULs. We performed cytogenetic analysis by G-banding in 10 cases undergoing myomectomy or hysterectomy. Fluorescence in situ hybridization (FISH) with a p53 gene probe was also used on interphase nuclei to screen for deletions. In patients, CAs were found in 23.4% of 500 cells analysed, significantly more frequent than in the control group (p<0.001). In the patients, 76% of the abnormalities were structural aberrations (deletions, translocations and breaks), and only 24% were numerical. Deletions were the most common structural aberration observed in CAs. Among these CAs, specific changes in five loci 1q11, 1q42, 2p23, 5q31 and Xp22 have been found in our patients and these changes were not reported previously in UL. The chromosome breaks were more frequent in cases, from high to low, 1, 2, 6, 9, 3, 5, 10 and 12. Chromosome 22, X, 3, 17 and 18 aneuploidy was observed to be the most frequent among all numerical aberrations. We observed a low frequency of p53 losses (2-11%) in our cases. The increased incidence of autosomal deletions, translocations, chromatid breaks and aneuploidy, could contribute to the progression of the disease along with other chromosomal alterations.

Keywords

Author Keywords

Uterine myomaschromosomal aberrationsFISHp53 genefamilial leiomyomatosisTurkey
 

Keywords Plus

TUMOR-SUPPRESSOR GENESQUAMOUS-CELL CARCINOMASCOMPARATIVE GENOMIC HYBRIDIZATIONMOLECULAR CYTOGENETIC ANALYSISSMOOTH-MUSCLE TUMORSABNORMALITIESEXPRESSIONIDENTIFICATIONREARRANGEMENTSABERRATIONS

Increased Density of Demodex folliculorum Mites in Pregnancies with Gestational Diabetes

By

Kurt, RK (Kurt, Raziye Keskin) [1] ; Kaya, OA (Kaya, Ozlem Aycan) [2] ; Karateke, A (Karateke, Atilla) [1] ; Silfeler, DB (Silfeler, Dilek Benk) [1] ; Karapinar, OS (Karapinar, Oya Soylu) [1] ; Akkoca, AN (Akkoca, Ayse Neslin) [3] ; Hakverdi, AU (Hakverdi, Ali Ulvi) [1]

 (provided by Clarivate) 

Source

MEDICAL PRINCIPLES AND PRACTICE

Volume

23

Issue

4

Page

369-372

DOI

10.1159/000363244

Published

2014

Indexed

2014-08-27

Document Type

Article

Abstract

Objective: To investigate the presence of Demodex in patients with gestational diabetes and the impact of glucose regulation on Demodex density in gestational diabetes. Subjects and Methods: The study population consisted of 33 patients with gestational diabetes and 30 pregnant women without gestational diabetes (control group). The age, parity, gestational age, and BMI of the study group were recorded and the patients were divided into 2 groups, i. e. those with regulated and unregulated glucose levels, according to their postprandial 1st-and 2nd-hour glucose values. A standardized skin surface biopsy method was used to determine if patients had Demodex folliculorum infestation (> 5 mites/cm 2 of skin). Results: Patients with gestational diabetes had a statistically significantly higher Demodex density compared to the control group (24.2 vs. 3.3%; p < 0.001). Furthermore, a significantly higher proportion of gestational diabetes patients with unregulated glucose levels had a higher Demodex density compared to those in the regulated subgroup (6/19 vs. 2/14; p = 0.001). Conclusion: Our study revealed that the Demodex density was increased in gestational diabetes patients. Further, poor glucose regulation could be the mechanism responsible for the increased Demodex density in gestational diabetes patients with unregulated glucose levels compared to those with regulated glucose levels. (C) 2014 S. Karger AG, Basel

Keywords

Author Keywords

Demodex folliculorumGestational diabetesPregnancy
 

Keywords Plus

INFESTATIONPREVALENCEROSACEABREVIS

CAN THE DUCTUS VENOSUS DOPPLER PREDICT THE HEMOGLOBINOPATHIES?

By

Karateke, A (Karateke, Atilla) [1] ; Silfeler, DB (Silfeler, Dilek Benk) [2] ; Güngören, A (Gungoren, Arif) [2] ; Kurt, RK (Kurt, Raziye Keskin) [2] ; Okyay, AG (Okyay, Ayse Guler) [2] ; Dokuyucu, R (Dokuyucu, Recep) [4] ; Ulutas, T (Ulutas, Turker) [5] ; Un, B (Un, Burak) [6] ; Paksoy, H (Paksoy, Hacer) [3] ; Hakverdi, AU (Hakverdi, Ali Ulvi) [2]

 (provided by Clarivate) 

Source

INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE

Volume

8

Issue

3

Page

4405-4409

Published

2015

Indexed

2015-07-02

Document Type

Article

Abstract

Objective: The aim of our study was to investigate the ductus venosus doppler between 11-13+6 (weekday) in pregnant women with hemoglobinopaties and its relation with fetal outcomes. Material and methods: A total of 100 pregnant women with hemoglobinopathies and 100 healthy pregnant women were included in our study. Ultrasonography (USG) was performed to all pregnant women and the ductus venosus doppler (DVD) flows were evaluated. The results were statistically analyzed. Results: The mean hemoglobin level was significantly lower in hemoglobinopathy group (9.7 +/- 0.7) than control group (10.67 +/- 0.82) (P<0.001). There was a significant relationship between Vmax, Vmin, S/D and reverse 'a' wave in fetuses with hemoglobinopathies. Vmax, Vmin and S/D parameters were higher in the group of hemoglobinopathies (respectively mean value, 31.3 +/- 1.66, 8.90 +/- 0.81, 2.97 +/- 0.49). Reverse 'a' wave was detected especially in all fetuses with sickle cell anemia. There was no significantly relationship between the groups in terms of PI, RI and HR. In a logistic regression analyses, fetal hemoglobinopathy was independently associated with Vmin (beta = 1.07, P = 0.001), S/D (beta = 2.61, P = 0.001) and reverse 'a' wave (beta = 2.46, P = 0.004). Conclusion: Pregnant women with hemoglobinopathies had changed ductus venosus doppler values in compared to normal pregnant women. Maternal anemia may cause this doppler changes. Furthermore all fetuses with sickle cell anemia (n = 5) had abnormal ductus venosus doppler findings. Further studies are needed to investigate the relationship between abnormal ductus venosus doppler findings and fetuses diagnosed with sickle cell anemia.

Keywords

Author Keywords

Hemoglobinopathiesductus venosus dopplerultrasonography
 

Keywords Plus

BLOOD-FLOWCARDIAC DEFECTSPREGNANCYFETUSES1ST-TRIMESTERVELOCIMETRYOUTCOMES

PREVALENCE OF CERVICAL CYTOLOGICAL ABNORMALITIES IN TURKEY

By

Kara, F (Kara, Fadil) [1] ; Kiran, G (Kiran, Guerkan) [2] ; Metindir, J (Metindir, Jale) [3] ; Ozan, H (Ozan, Hakan) [4] ; Özalp, S (Ozalp, Sinan) [5] ; Vardar, MA (Vardar, M. Ali) [6] ; Zeren, H (Zeren, Handan) [6] ; Dilek, S (Dilek, Saffet) [7] ; Bozkaya, H (Bozkaya, Hasan) [8] ; Güven, S (Guven, Sueleyman) [8] ; 

Group Author

Turkish Cervical Canc Cervical Cyt (Turkish Cervical Canc Cervical Cyt)

 (provided by Clarivate) 

Source

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS

Volume

106

Issue

3

Page

206-209

DOI

10.1016/j.ijgo.2009.04.003

Published

SEP 2009

Indexed

2009-09-01

Document Type

Article

Abstract

Objective: To evaluate retrospectively the prevalence of cervical cytological abnormalities in patient records obtained from healthcare centers in Turkey. Method: Demographic characteristics and data on cervical cytological abnormalities were evaluated from patients who underwent flap tests in healthcare centers in 2007. Results: Data were collected from 33 healthcare centers totaling 140 334 patients. Overall, the prevalence of cervical cytological abnormalities was 1.8%; the prevalence of ASCUS, ASC-H, LSIL, HSIL, and AGC was 1.07%, 0.07%, 0.3%, 0.17%, and 0.08%, respectively. The prevalence of preinvasive cervical neoplasia was 1.7% and the prevalence of cytologically diagnosed invasive neoplasia was 0.06%. Conclusion: The abnormal cervical cytological prevalence rate in Turkey is lower than in Europe and North America. This might be due to sociocultural differences, lack of population-based screening programs, or a lower HPV prevalence rate in Turkey. (C) 2009 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

Keywords

Author Keywords

Cervical cancerCervical cytologyCervical intraepithelial neoplasiasCervical neoplasiasPap testPap smearTurkey
 

Keywords Plus

CERVICOVAGINAL CYTOLOGYCOMPARISON PROGRAMPARTICIPANTSCANCERWOMENRISK

1. TÜRK ONKOLOJİ DERNEĞİ, Üye , 2010
2. TÜRK ÜROJİNEKOLOJİ VE PELVİK REKONSTRÜKTİF CERRAHİ DERNEĞİ, Üye , 2006
3. TJOD, Üye , 1993