Tınaztepe

Op. Dr. Ulaş Aktaş

Görev Aldığı Bölümler Beyin ve Sinir Cerrahisi
Görev Aldığı Lokasyonlar İzmir Tınaztepe Üniversitesi Özel Buca Hastanesi

Eğitimi: Uludağ Üniversitesi Tıp Fakültesi 1996/2004  BURSA

Uzmanlık Eğitimi: Uludağ Üniversitesi Tıp Fakültesi Nöroşirurji ABD. BURSA 2004/2011

  • Uludağ Üniversitesi Tıp Fakültesi Nöroşirurji ABD. Araştırma Görevlisi  BURSA 2004/2011
  • Sağlık Bakanlığı Ergani Devlet Hastanesi Ergani/DİYARBAKIR  

2012 Mayıs-2012 Kasım                                                                    

  • Gazi Yaşargil Eğitim ve Araştırma Hastanesi  DİYARBAKIR

2012 Kasım- 2019 Ocak

  • SBÜ Gazi Yaşargil Eğitim ve Araştırma Hastanesi  DİYARBAKIR

2019 Ocak- 2021 Haziran

  • Tınaztepe Buca Hastanesi İZMİR

2021 Temmuz’dan itibaren çalışmaya devam etmekte

Araştırmalar ve Yayınlar:

1-Thoracolumbar İnterfascial Plane Block with the Application of Local Anesthesia in the Management of Postoperative Pain in Patients with Lomber Disk Surgery       

Bicak M, Aktas U, Salik F, Akelma H, Bicak EA, Kaya S.

Turk Neurosurg. 2021;31(5):757-762. doi: 10.5137/1019-5149

2-Paraplegia Due to Spinal Cord Infarction After Coronary Artery Bypass Graft Surgery.

Sevuk U, Kaya S, Ayaz F, Aktas U.

J Card Surg. 2016 Jan;31(1):51-6. doi: 10.1111/jocs.12666. Epub 2015 Nov 10

 

3-Spondylodiscitis: evaluation of patients in a tertiary hospital.

Kaya S, Ercan S, Kaya S, Aktas U, Kamasak K, Ozalp H, Cinar K, Duymus R, Boyaci MG, Akkoyun N, Eskazan AE, Temiz H.

J Infect Dev Ctries. 2014 Oct 15;8(10):1272-6

 

4-Multiple extracranial metastases from secondary glioblastoma: a case report and review of the literature.

Taskapilioglu MO, Aktas U, Eser P, Tolunay S, Bekar A.

Turk Neurosurg. 2013;23(6):824-7

 

5-Odontoid kırıklarında C1-C2 posterior  stabilizasyon.

 Taşkapılıoğlu Ö, Başaran E, Aktaş U, Doğan Ş.

The Journal of Turkish Spinal Surgery. 2013 Apr  24;2 : 135-141

 

6-Anatomical restrictions in the transsphenoidal, transclival approach to the upper clival region: a cadaveric, anatomic study.

Aktas U, Yilmazlar S, Ugras N.

J Craniomaxillofac Surg. 2013 Sep;41(6):457-67.

 

7- A Case of Spınal Intradural Extramedullary Hydatıd Cyst Mımıckıng a Spınal Tumor.

Özmen A,Bekar A,Tolunay  Ş, Heper Y, Yılmaz E, Helvacı S, Zorlu S, Aktaş U.

Türkiye Klinikleri Tıp Bilimleri Dergisi  33(2) 572-575, 2013

 

8-Olfaktor oluk meningiomalarında klinik deneyimler.

Yılmazlar S, Aktas U, Kaplan T, Işık S, Eser P

Uludağ Üniversitesi Tıp Fakültesi Dergisi 38(1) 19-23, 2012

 

9-Effect of Reoperation on Survival of Patients With Glioblastoma.

 Bekar A, Taşkapılıoğlu Ö, Moralı T,  Kuytu T,  Aktaş U, Kaplan T, Tolunay Ş.

Journal of Neurological Sciences [Turkish] 29:(1) 30; 000-000, 2012

 

10-Lumbal facet cyst a case report.

Taşkapılıoğlu Ö, Aktaş U, Güler T, Korfalı E.

The Journal of Turkish Spinal Surgery.  22(2) 137-140, 2011

 

Kurs Katılımları:

1-Enteral ve Parenteral Beslenme Kursu. Uludağ Üniversitesi Tıp Fakültesi, BURSA 2005

2- Enteral ve Parenteral Beslenme Kursu. Uludağ Üniversitesi Tıp Fakültesi, BURSA 2009

3-Klinik Laboratuar İlişkileri Kursu. Uludağ Üniversitesi Tıp Fakültesi, BURSA 2009

4-Temel ve İleri Yaşam Desteği Kursu. Uludağ Üniversitesi Tıp Fakültesi, BURSA 2010

5-Travmalı Hastaya Acil Yaklaşım Kursu. Uludağ Üniversitesi Tıp Fakültesi, BURSA 2010

6-Klinik Araştırmalar Kursu. Uludağ Üniversitesi Tıp Fakültesi, BURSA 2010

7-Kan Ürünleri Kullanım Kursu. Uludağ Üniversitesi Tıp Fakültesi, BURSA 2010

8-Hastane Enfeksiyonları Kursu. Uludağ Üniversitesi Tıp Fakültesi, BURSA 2010

9-Spinal ve Periferik Sinir Cerrahisi Yaz Okulu Kursu. Türk Nöroşirurji Derneği Spinal ve Periferik Sinir Cerrahisi Öğretim ve Eğitim Grubu, Sapanca 2011

10-Organ Bağışında Uyum İçin Teknik Yardım Kursu. DİYARBAKIR 2015

 

ChatGPT-4o's Performance in Brain Tumor Diagnosis and MRI Findings: A Comparative Analysis with Radiologists


By

Ozenbas, C (Ozenbas, Cemre) [1] ; Engin, D (Engin, Duygu) [2] ; Altinok, T (Altinok, Tayfun) [1] ; Akcay, E (Akcay, Emrah) [3] ; Aktas, U (Aktas, Ulas) [4] ; Tabanli, A (Tabanli, Alper) [4]

 (provided by Clarivate) 

Source

ACADEMIC RADIOLOGY

Volume

32

Issue

6

Page

3608-3617

DOI

10.1016/j.acra.2025.01.033

Published

JUN 2025

Early Access

MAY 2025

Indexed

2025-06-17

Document Type

Article

Jump to

Abstract

Rationale and objectives: To evaluate the accuracy of ChatGPT-4o in identifying magnetic resonance imaging (MRI) findings and diagnosing brain tumors by comparing its performance with that of experienced radiologists. Materials and methods: This retrospective study included 46 patients with pathologically confirmed brain tumors who underwent preoperative MRI between January 2021 and October 2024. Two experienced radiologists and ChatGPT 4o independently evaluated the anonymized MRI images. Eight questions focusing on MRI sequences, lesion characteristics, and diagnoses were answered. ChatGPT-4o's responses were compared to those of the radiologists and the pathology outcomes. Statistical analyses were performed, which included accuracy, sensitivity, specificity, and the McNemar test, with p<0.05 considered to indicate a statistically significant difference. Results: ChatGPT-4o successfully identified 44 of the 46 (95.7%) lesions; it achieved 88.3% accuracy in identifying MRI sequences, 81% in perilesional edema, 79.5% in signal characteristics, and 82.2% in contrast enhancement. However, its accuracy in localizing lesions was 53.6% and that in distinguishing extra-axial from intra-axial lesions was 26.3%. As such, ChatGPT-4o achieved success rates of 56.8% and 29.5% for differential diagnoses and most likely diagnoses when compared to 93.2-90.9% and 70.5-65.9% for radiologists, respectively (p<0.005). Conclusion: ChatGPT-4o demonstrated high accuracy in identifying certain MRI features but underperformed in diagnostic tasks in comparison with the radiologists. Despite its current limitations, future updates and advancements have the potential to enable large language models to facilitate diagnosis and offer a reliable second opinion to radiologists.

Keywords

Author Keywords

Artificial intelligence ChatGPT-4o Brain tumor MRI

 

Comparison of Thoracolumbar Interfascial Plane Block with the Application of Local Anesthesia in the Management of Postoperative Pain in Patients with Lumbar Disc Surgery


By

Bicak, M (Bicak, Mustafa) [1] ; Aktas, U (Aktas, Ulas) [2] ; Salik, F (Salik, Fikret) [1] ; Akelma, H (Akelma, Hakan) [1] ; Bicak, EA (Bicak, Esra Aktiz) [1] ; Kaya, S (Kaya, Sedat) [1]

 (provided by Clarivate) 

Source

TURKISH NEUROSURGERY

Volume

31

Issue

5

Page

757-762

DOI

10.5137/1019-5149.JTN.33017-20.2

Published

2021

Indexed

2021-11-12

Document Type

Article

Abstract

AIM: To compare the effect of ultrasound-guided modified thoracolumbar interfascial plane (TLIP) block versus local anesthetic infiltration on the wound site for post-operative analgesia in patients undergoing lumbar disc surgery with spinal anesthesia.

MATERIAL and METHODS: This prospective and observationally planned study included 42 patients from the ages of 18 to 75 years, American Society of Anesthesiologists classes I-III, who underwent lumbar disc surgery. In Group L, bupivacaine infiltration was performed on the surgical incision line. In Group T, TLIP block was performed with ultrasound. In the postoperative period, visual analogue scale (VAS) values were also investigated and recorded on the 10th day after discharge. Nausea, vomiting, and sedation score values and analgesic doses used by all patients in the postoperative period were recorded.

RESULTS: During any of the postoperative follow-up hours, the VAS score was <= 3 (mild pain), and those who did not need tramadol were 80.9% (n=17) in Group T and 71.4% (n=15) in Group L. VAS scores at the 1st, 4th, and 8th hours were statistically lower in Group L than those in Group T (p values: 0.011, 0.028, and 0.029). The average amounts of tramadol consumption per patient were determined as 19.04 mg +/- 40.23 in Group T and 27.38 +/- 44.65 mg in Group L in the first 24 hours postoperatively. There was no statistically significant difference between groups (p=0.519).

CONCLUSION: In this study, it was determined that the modified TLIP block application performed for the purpose of post-operative analgesia in lumbar disc surgery was not superior to local anesthetic infiltration in terms of postoperative opioid consumption and VAS scores.

Keywords

Author Keywords

Thoracolumbar interfascial plane block Local anesthesia Postoperative pain Lomber disc surgery

Measuring the knowledge and attitudes of physicians towards patients with HIV/AIDS: study of Anatolian group


By

Kaya, S (Kaya, Safak) [1] ; Arac, E (Arac, Esref) [2] ; Akgul, F (Akgul, Fethiye) [3] ; Comoglu, S (Comoglu, Senol) [4] ; Kaya, S (Kaya, Sehmuz) [5] ; Araç, S (Arac, Songul) [6] ; Yildiz, Y (Yildiz, Yesim) [7] ; Buyuktuna, SA (Buyuktuna, Seyit Ali) [8] ; Kayaaslan, B (Kayaaslan, Bircan) [9] ; Parlak, E (Parlak, Emine) [10] ; 

 (provided by Clarivate) 

Source

INTERNATIONAL JOURNAL OF HUMAN RIGHTS IN HEALTH CARE

Volume

17

Issue

1

Page

11-16

DOI

10.1108/IJHRH-10-2020-0093

Published

FEB 20 2024

Early Access

MAY 2021

Indexed

2021-05-14

Document Type

Article

Abstract

Purpose

This paper aims to determine the knowledge and attitudes of the physicians regarding human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS), to emphasize that these patients exist and they will exist in the future and to raise awareness so as to prevent that their rights to treatment are revoked.

Design/methodology/approach

The survey was conducted via a link sent through an online system. Random physicians from 81 cities of the country were invited to the survey. The survey has 41 questions regarding knowledge and attitudes in total, including epidemiological information such as age, gender and title.

Findings

A total of 3,107 physicians has voluntarily participated in the study. In total, 2,195 (70.7%) are internal physicians and 912 (29.3%) are surgical physicians among the participant physicians. In total, 1,452 (46.7%) of the participants are specialist physicians, 608 (19.6%) of the participants are practising physician and the rest of it is physician assistants, academicians and dentists, respectively.

Originality/value

In this study, it has been found out that the physicians have a lack of knowledge on HIV/AIDS and they adopt a discriminatory attitude towards HIV-positive persons. HIV-positive patients who are exposed to discrimination and scared of being uncovered refrain from applying to hospitals for treatment, which puts public health into jeopardy due to the high viral load and these patients are faced with difficulties in coping with both medical and emotional load of the disease.

Keywords

Author Keywords

HIV Physician Discrimination AIDS

 

Paraplegia Due to Spinal Cord Infarction After Coronary Artery Bypass Graft Surgery


By

Sevuk, U (Sevuk, Utkan) [1] ; Kaya, S (Kaya, Sedat) [2] ; Ayaz, F (Ayaz, Firat) [1] ; Aktas, U (Aktas, Ulas) [3]

 (provided by Clarivate) 

Source

JOURNAL OF CARDIAC SURGERY

Volume

31

Issue

1

Page

51-56

DOI

10.1111/jocs.12666

Published

JAN 2016

Indexed

2016-01-27

Document Type

Review

Abstract

Paraplegia is an extremely rare complication after coronary artery bypass grafting (CABG) and the underlying mechanisms remain poorly understood. We report a patient who developed paraplegia after CABG and review the literature on spinal cord ischemia following CABG surgery. doi: 10.1111/jocs.12666 (J Card Surg 2016;31:51-56)

Keywords

Keywords Plus

BALLOON PUMPAORTIC DISSECTION ISCHEMIA COMPLICATIONS INJURY

 

Anatomical restrictions in the transsphenoidal, transclival approach to the upper clival region: A cadaveric, anatomic study


By

Aktas, U (Aktas, Ulas) [1] ; Yilmazlar, S (Yilmazlar, Selcuk) [1] ; Ugras, N (Ugras, Nesrin) [2]

 (provided by Clarivate) 

Source

JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY

Volume

41

Issue

6

Page

457-467

DOI

10.1016/j.jcms.2012.11.011

Published

SEP 2013

Indexed

2013-11-05

Document Type

Article

Abstract

Objective: Tumours in the clival region are difficult to remove surgically. Before the 1970s, clival tumours had very high mortality and morbidity rates.

Methods: An anatomic dissection was performed on 24 spheno-occipital bone blocks obtained from 28 adult cadavers. The internal carotid artery, paraclival carotid tubercle, sixth cranial nerve and dorsum sellae in the upper clival region were analyzed qualitatively and quantitatively. For the histological evaluation, 4 samples were decalcified and sagittal sections were cut. From the eight blocks obtained, 32 incisions were made in the axial plane, and the tissue was analyzed.

Results: Using microscopy, a clival recess was clearly identified in 15 of the 24(62.5%) samples. Paraclival carotid tubercles were observed in 19 (79.16%) of the samples. In the upper clival and petroclival region, the sixth cranial nerve had directional changes at the dural porus, the petrous apex and the lateral wall of the cavernous segment of the internal carotid artery. At the dorsum sellae level, the distance between the medial surfaces of both internal carotid arteries was a mean of 15.33 +/- 2.12 mm. This distance at the pharyngeal tubercle was a mean of 38.95 +/- 4.67 mm. On all the histological sections, the distance of the sixth cranial nerve from the dural porus to the cavernous sinus was within the basilar plexus, along with the subarachnoid membranes around it. On the petrous apex level, the sixth cranial nerve was fixed to the petrous apex and the internal carotid artery with connective tissue formed by dense collagen fibres. The sixth cranial nerve and the internal carotid artery are tightly surrounded by dense collagen connective tissue, and the relative proximity between the carotids on the dorsum sellae level can be easily damaged during the transsphenoidal-transclival approach. Similarly, due to the ligamentous fixation on the dural porus and the petrous apex surfaces, there is a high risk of injury to the carotid artery and sixth cranial nerve.

Conclusion: This study determines the relationship between the sixth cranial nerve and the internal carotid artery at the upper clivus and to provide morphologic details that is essential for the risks of transclival surgery. (C) 2012 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

Keywords

Author Keywords

Upper clivus Anatomy Abducent nerve Transsphenoidal-trans clival approach Internal carotid artery

 

Spondylodiscitis: evaluation of patients in a tertiary hospital


By

Kaya, S (Kaya, Safak) [1] ; Ercan, S (Ercan, Serdar) [2] ; Kaya, S (Kaya, Sehmuz) [3] ; Aktas, U (Aktas, Ulas) [2] ; Kamasak, K (Kamasak, Kagan) [2] ; Ozalp, H (Ozalp, Hakan) [4] ; Cinar, K (Cinar, Kadir) [5] ; Duymus, R (Duymus, Recai) [6] ; Boyaci, MG (Boyaci, Mehmet Gazi) [7] ; Akkoyun, N (Akkoyun, Nesrin) [8] ; 

 (provided by Clarivate) 

Source

JOURNAL OF INFECTION IN DEVELOPING COUNTRIES

Volume

8

Issue

10

Page

1272-1276

DOI

10.3855/jidc.4522

Published

OCT 2014

Indexed

2014-10-01

Document Type

Article

Abstract

Introduction: Spondylodiscitis (SD) is an uncommon but important infection. The aim of this work was to study the risk factors, bacteriological features, clinical, laboratory and radiological findings of SD, and to shed light on the initial treatment.

Methodology: A total of 107 patients who underwent treatment for SD were evaluated. The diagnosis of SD was defined by clinical findings, complete blood count, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), serum tube agglutination (STA) test, Ziehl-Neelsen staining, culture, histopathology, and radiological methods such as magnetic resonance imaging (MRI) and computed tomography (CT) scans.

Results: Of the 107 cases, ranging between 17 to 83 years of age, 64 (59.8%) were male. Twenty-seven (25.2%) patients had diabetes mellitus. Laboratory investigations revealed elevated CRP in 70 (65%) patients, elevated ESR in 65 (61%) patients, and elevated white blood cell (WBC) counts in 41 (38.3%) patients. Thirty-six (33.6%) patients were identified as having brucellar SD, and 5 (4.7%) patients were identified as having tuberculous SD. A total of 66 (61.6%) patients were determined to have pyogenic SD. The most frequently isolated microorganism was Staphylococcus aureus. Antibiotic therapy was given intravenously to all pyogenic SD patients.

Conclusions: The incidence of SD has increased as a result of the higher life expectancy of older patients with chronic debilitating diseases and the increase of spinal surgical procedures. In patients with low back pain, SD should be considered as a diagnosis. For effective treatment, it is important to determine the etiology of the disease.

Keywords

Author Keywords

spondylodiscitis brucellosis tuberculous pyogenic postoperative

 

Multiple Extracranial Metastases from Secondary Glioblastoma: A Case Report and Review of the Literature


By

Taskapilioglu, MO (Taskapilioglu, Mevlut Ozgur) [1] ; Aktas, U (Aktas, Ulas) [1] ; Eser, P (Eser, Pinar) [1] ; Tolunay, S (Tolunay, Sahsine) [2] ; Bekar, A (Bekar, Ahmet) [1]

 (provided by Clarivate) 

Source

TURKISH NEUROSURGERY

Volume

23

Issue

6

Page

824-827

DOI

10.5137/1019-5149.JTN.6497-12.1

Published

NOV 2013

Indexed

2014-02-05

Document Type

Review

Abstract

Glioblastoma represents extreme anaplasia in astrocytic tumors. In spite of this aggressiveness, extracranial metastasis of glioblastoma is very rare and has been documented in only a few patients in the literature. In this article, a 30-year-old woman with secondary glioblastoma associated with extracranial distant metastasis was presented. In September 2008, an intracranial lesion in the left frontal region was diagnosed by magnetic resonance imaging (MRI) after admission to the hospital by headache and seizure and subsequently resected. The histology of the lesion revealed an anaplastic astrocytoma (grade III). Upon recurrence of the tumor 7 months later, the patient underwent a second craniotomy for recurrence tumor resection. The histological diagnosis was glioblastoma. After radiotherapy and chemotherapy, cranial computerized tomography (CT) and whole body scintigraphy revealed metastatic lesions in the right cervical lymph nodes and the left ischium. A neck dissection and parathyroidectomy on the right side was performed. The cytomorphological and histological features of the tumor supported the diagnosis of metastatic glioblastoma.

Keywords

Author Keywords

Glioblastoma Extracranial metastasis Secondary glioblastoma Prognosis

 

Effect of Reoperation on Survival of Patients With Glioblastoma


By

Bekar, A (Bekar, Ahmet) [1] ; Taskapilioglu, MO (Taskapilioglu, Mevlut Ozgur) [1] ; Güler, TM (Guler, Tugba Morali) [1] ; Aktas, U (Aktas, Ulas) [1] ; Tolunay, S (Tolunay, Sahsine) [1]

 (provided by Clarivate) 

Source

JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH

Volume

29

Issue

1

Page

110-116

Published

2012

Indexed

2012-06-13

Document Type

Article

Abstract

Objective: Surgical resection is the most important part of glioblastoma treatment. The objective of this study was to determine the effect of reoperation on survival of patients with glioblastoma.

Methods: Records of the glioblastoma patients operated between 2001 and 2010 by the senior author were analyzed retrospectively. Comparisons were made between patients who received ( Reoperation group, n=50) and who did not receive (Monooperation group, n=111) reoperation with regard to age, gender, tumor localization, number of operations and length of survival.

Results: No significant difference was found between two groups in terms of age, gender, and tumor localization. Mean follow-up duration was 12.7 months (range: 1-96 month). Mean lengths of survival after the first operation were 26.7 +/- 4.0 months and 12.2 +/- 1.6 months in the reoperation and monooperation groups, respectively (p<0.001). Regression analysis revealed that reoperation was the only prognostic factor determining the survival in recurrent malignant glial tumors. Moreover, surgical site was shown to affect survival; rate of mortality in patients operated on temporal side was statistically greater than that in patients operated on parietal side (p=0.01).

Conclusion: Despite modern treatment strategies, reoperation is still the most important factor determining the length of survival in recurrent glioblastoma.

Keywords        Glioblastoma reoperation survival

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