GÖREV ALDIĞI BÖLÜMLER
FİZİK TEDAVİ VE REHABİLİTASYON
Brain morphometric changes in patients with fibromyalgia
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JOURNAL OF THE PAKISTAN MEDICAL ASSOCIATION
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The aim of this study was to determine whether there is a decrease or an increase in the volume of different regions of the brain by comparing brain morphometry ofpatients diagnosed with Fibromyalgia Syndrome and healthy control subjects.The study included 23 female patients who were diagnosed with fibromyalgia, and 18 females, age -matched healthy subjects. Structural Mitral Regurgitation data was processed using Surface-Based Morphometry (SBM) on the Freesurfer 6.0 programme (http://surfer.nmr.mgh.harvard.edu).As a result of the surface-based analyses, a statistically significant reduction was determined in the Fibromyalgia Syndrome patient group in some brain region. A statistically signficant increase was determined in the FMS patient group with respect to the left anterior occipital sulcus volume, left inferior temporal gyrus thickness and left anterior occipital sulcus area.The results of this study showed that FMS affected brain morphometry through the brain central pain mechanisms and the normal brain morphology was changed because of atrophy in some areas and hypertrophy in some areas.
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Author Keywords
Brain MRI Brain morphometry Fibromyalgia pain
Correlation of Brain Magnetic Resonance Spectroscopy and Diffusion Tensor Imaging with the Severity of Clinical Symptoms in Fibromyalgia Patients
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IRANIAN JOURNAL OF RADIOLOGY
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Background: Fibromyalgia is recognized as a chronic pain syndrome. Widespread pain is a common symptom in fibromyalgia, indicating a potential dysfunction in the processing of painful sensations in the central nervous system.Objectives: This study aimed to investigate changes in the severity of clinical symptoms in fibromyalgia patients and to evaluate the apparent diffusion coefficients and metabolites in the brain of these patients. Patients and Methods: This cross-sectional study included 28 female outpatients with complaints of widespread pain, who were diagnosed with fibromyalgia syndrome. Magnetic resonance imaging, magnetic resonance spectroscopy, and diffusion tensor ex-aminations were applied to evaluate patients diagnosed with fibromyalgia before treatment. Results: The mean age of the patients included in this study was 39.1 +/- 8.6 years (range, 24-55 years). A statistically significant strong positive correlation was found between the scores of the visual analog scale and the fibromyalgia impact questionnaire. Besides, significant associations were found between the scores of the visual analog scale and fibromyalgia impact questionnaire and the results of fractional anisotropy, apparent diffusion coefficient, and peak values of some metabolites in spectroscopy. Conclusion: The results of this study suggest that metabolites play an inhibitory or excitatory role in the central pain mechanisms of fibromyalgia as a chronic pain syndrome.
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Fibromyalgia Brain Magnetic Resonance Spectroscopy Diffusion Tensor Imaging Pain
Morphometric Analysis of the Glenoid Fossa in the Skull Base
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JOURNAL OF CRANIOFACIAL SURGERY
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Objective: The aim of this study was to investigate the possible relationship between disc displacement and the presence of reduction by comparing condyle anteroposterior (AP) diameter, condyle height, mandibular fossa AP diameter, and mandibular fossa depth.
Methods: A total of 588 joints of 294 patients were included in the study for evaluation. Disc displacement and the presence of reduction, condyle AP diameter, condyle height, mandibular fossa AP diameter, and mandibular fossa depth were evaluated.
Results: Of the 588 temporomandibular joint examined in the study, there was disc displacement in 141 (24%) and no disc displacement in 447 (76%). Of the joints with disc displacement, reduction was observed in 53 (9%) and not in 88 (15%).
A statistically significant correlation was determined between condyle AP diameter and disc displacement (P = 0.00); in the cases with disc displacement, the condyle AP diameter was measured smaller. A statistically significant correlation was determined with condyle height, mandibular fossa AP diameter, and fossa depth. In the patients with disc displacement, the condyle height value was lower and the measured values of the mandibular fossa AP diameter and mandibular fossa depth were higher (P = 0.00). A statistically significant relationship was determined between the presence of reduction and age, condyle AP diameter, condyle height, and articular eminence depth.
Conclusions: In conclusion, a deep and wide mandibular fossa, and a short and small condyle lay the ground for disc displacement in the temporomandibular joint.
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Magnetic resonance imaging mandibular condyle temporomandibular joint
Does diffusion-weighted magnetic resonance imaging have a place in the differential diagnosis of brucella sacroiliitis and seronegative spondyloarthropathy?
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ACTA RADIOLOGICA
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Background The aim of this study is to investigate the role of diffusion-weighted imaging (DWI) in the differential diagnosis of sacroiliitis. Purpose To compare the sacroiliac magnetic resonance imaging (MRI) examinations of patients with suspected active sacroiliitis with patients with acute SpA MR findings and the DWI examinations of patients with acute brucella sacroiliitis, and thereby determine whether DWI can contribute to the differential diagnosis. Material and Methods A total of 84 patients were included in the study and were separated into three groups: group 1 (13 women, 6 men) comprised cases with brucella positive for sacroiliitis; group 2 (17 women, 19 men) comprised cases negative for brucella but with sacroiliitis; and group 3 (16 women, 13 men) comprised cases negative for brucella and sacroiliitis. Results The mean bone marrow apparent diffusion coefficient (ADC) values independently of edema were determined as 0.71 x 10(-3)in sacroiliitis and brucella-positive patients, as 0.53 x 10(-3)in brucella-negative and sacroiliitis-positive patients, and as 0.43 x 10(-3)in the control group of brucella-negative sacroiliitis-negative patients. In the ADC measurements taken from areas of evident edema in patients with sacroiliitis, the mean values were 0.13 x 10(-3)in the brucella-positive group and 0.12 x 10(-3)in the brucella-negative group. Conclusion By adding DWI, which is a rapid MR sequence, to sacroiliac joint MR examination, normal bone marrow and bone marrow with sacroiliitis can be objectively differentiated with ADC measurements in addition to visual evaluation.
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Sacroiliitis brucella diffusion-weighted imaging