Tınaztepe

Op. Dr. Raşan Genç

Departments Ear Nose Throat
Locations İzmir Tınaztepe University Private Buca Hospital Tınaztepe Buca Medical Center

1999 Çukurova University Faculty of Medicine

1 year language training in London

2002-2005 Eskişehir Osmangazi University Chest Diseases

 

2006-2011 Erciyes University Faculty of Medicine ENT-Head and Neck Surgery

2011-2013 Nigde State Hospital

2013-Private Dunyam Hospital

 

The Role of H. pylori in the Development of Laryngeal Squamous Cell Carcinoma


By

Genc, R (Genc, Rasan) [1] ; Çagli, S (Cagli, Sedat) [2] ; Yüce, I (Yuce, Imdat) [2] ; Vural, A (Vural, Alperen) [3] ; Okuducu, H (Okuducu, Haci) [4] ; Patiroglu, T (Patiroglu, Tahir) [5] ; Güney, E (Guney, Ercihan) [2]

 (provided by Clarivate) 

Source

DISEASE MARKERS

Volume

2013

DOI

10.1155/2013/950701

Published

2013

Indexed

2013-01-01

Document Type

Article

Abstract

Aim. This study aims to investigate the possible role of H. pylori as a cause of laryngeal squamous cell carcinoma. Method. This controlled study was performed with 31 consecutive laryngeal cancer and 28 cancer-free patients who underwent direct laryngoscopy and biopsy of laryngeal lesions. To document the previous H. pylori infection, serological analysis of the antibody titers was done. Immunohistochemical analyses were applied to the tissue samples. Results. Serology was found positive at the 90.3% of the laryngeal cancer patients and 96.4% of the benign group. There were no statistically significant differences between the two groups (P > 0.05). Immunohistochemical analysis results were determined as negative at all of the specimens of laryngeal cancer patients and patients with benign lesions. Conclusion. There were no signs of colonization of H. pylori in laryngeal tissues of both groups' patients. It is thought that no relationship exists between the H. pylori infection and laryngeal squamous cell carcinoma.

Keywords

Keywords Plus

EARLY GASTRIC-CANCER HELICOBACTER-PYLORI INFECTION ASSOCIATION ETIOLOGY HEAD RISK

 

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